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| Cat.No | ACP15649 | Target Name | AMIGO2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86SJ2 |
|---|
Uniprot Id
Q86SJ2
Target Species
Human
Target Name
AMIGO2
Target Full Name
Amphoterin-induced protein 2
Target Function
Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Nucleus.
Target Protein Families
Immunoglobulin superfamily, AMIGO family
Target Tissue Specificity
Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.
Target Synonyms
Adhesion molecule with Ig like domain 2; ALI 1; ALI1; Alivin 1; Alivin-1; Alivin1; AMGO2_HUMAN; AMIGO 2; AMIGO-2; Amigo2; Amphoterin induced gene 2; Amphoterin induced protein 2; Amphoterin-induced gene and open reading frame 2; Amphoterin-induced protein 2; DEGA; Differentially expressed in gastric adenocarcinoma; Differentially expressed in gastric adenocarcinomas; Transmembrane protein AMIGO 2; Transmembrane protein AMIGO2
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