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| Cat.No | ACP13619 | Target Name | ZFAND1 |
|---|---|---|---|
| Target Synonyms | ZFAND1AN1-type zinc finger protein 1; Zinc finger AN1-type-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-268 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TCF1 |
|---|
Uniprot Id
Q8TCF1
Target Species
Human
Target Name
ZFAND1
Target Full Name
AN1-type zinc finger protein 1
Target Function
Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress. Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome. This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during recovery from arsenite stress, and hence avoiding aberrant cytoplasmic SGs degradation via autophagy
Target Subcellular Location
Cytoplasm, Stress granule.
Target Synonyms
ZFAND1AN1-type zinc finger protein 1; Zinc finger AN1-type-containing protein 1
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