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| Cat.No | ACP04287 | Target Name | ANAPC15 |
|---|---|---|---|
| Target Synonyms | ANAPC15; C11orf51; HSPC020Anaphase-promoting complex subunit 15; APC15 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-121aa |
| Mol Weight | 41.3kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P60006 |
|---|
Uniprot Id
P60006
Target Species
Human
Target Name
ANAPC15
Target Full Name
Anaphase-promoting complex subunit 15
Target Function
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.
Target Protein Families
APC15 family
Target Research Area
Cell Biology
Target Synonyms
ANAPC15; C11orf51; HSPC020Anaphase-promoting complex subunit 15; APC15
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