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Recombinant Human Angiopoietin-like protein 8 (ANGPTL8)

ACP05169

Number
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Specifications


Cat.No ACP05169 Target NameAngptl8
Target SynonymsANGPTL8; C19orf80; RIFL; UNQ599/PRO1185Angiopoietin-like protein 8; Betatrophin; Lipasin; Refeeding-induced fat and liver proteinFormLiquid or Lyophilized powder
Expression SystemBaculovirusExpression Range22-198aa
Mol Weight22.4 kDaProtein LengthFull Length of Mature Protein
PurityGreater than 85% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6UXH0
Background Information
  • Uniprot Id

    Q6UXH0

  • Target Species

    Human

  • Target Name

    ANGPTL8

  • Target Full Name

    Angiopoietin-like protein 8

  • Target Function

    Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state.

  • Target Involvement

    Diabetes mellitus, insulin-dependent (IDDM); Diabetes mellitus, non-insulin-dependent (NIDDM)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    ANGPTL8 family

  • Target Tissue Specificity

    Predominantly expressed in liver. Also expressed in adipose tissues.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185Angiopoietin-like protein 8; Betatrophin; Lipasin; Refeeding-induced fat and liver protein

  • Target Background

    Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region.

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