Home Products Recombinant Human Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2), Truncated

Recombinant Human Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2), Truncated

ACP15546

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Specifications

Cat.No	ACP15546	Target Name	ANKLE2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q86XL3

Background Information

Uniprot Id

Q86XL3
Target Species

Human
Target Name

ANKLE2
Target Full Name

Ankyrin repeat and LEM domain-containing protein 2
Target Function

Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. May regulate nuclear localization of VRK1 in non-dividing cells. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development.
Target Involvement

Microcephaly 16, primary, autosomal recessive (MCPH16)
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Target Protein Families

ANKLE2 family
Target Synonyms

ANKL2_HUMAN; ANKLE 2 ; ANKLE2; ankyrin repeat and LEM domain containing 2; Ankyrin repeat and LEM domain-containing protein 2; FLJ 22280; FLJ 36132; FLJ22280; FLJ36132; KIAA 0692; KIAA0692; LEM domain containing 7; LEM domain-containing protein 4; LEMD 7 ; LEMD7

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Recombinant Human Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2), Truncated Now

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