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| Cat.No | ACP13576 | Target Name | ASB10 |
|---|---|---|---|
| Target Synonyms | ASB10Ankyrin repeat and SOCS box protein 10; ASB-10 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-467 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WXI3 |
|---|
Uniprot Id
Q8WXI3
Target Species
Human
Target Name
ASB10
Target Full Name
Ankyrin repeat and SOCS box protein 10
Target Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Target Involvement
Glaucoma 1, open angle, F (GLC1F)
Target Subcellular Location
Cytoplasm. Nucleus. Note=In the ciliary body, it is detected in the cytoplasm and perinuclear region of the pigmented ciliary epithelial layer. In the retina, it is detected in the nuclei of retinal ganglion cells.
Target Protein Families
Ankyrin SOCS box (ASB) family
Target Tissue Specificity
Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve; slightly lower levels in the ciliary body, retina, and choroid; and very low levels in the lens.
Target Synonyms
ASB10Ankyrin repeat and SOCS box protein 10; ASB-10
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