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| Cat.No | ACP09755 | Target Name | ASB3 |
|---|---|---|---|
| Target Synonyms | ASB3Ankyrin repeat and SOCS box protein 3; ASB-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-518 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y575 |
|---|
Uniprot Id
Q9Y575
Target Species
Human
Target Name
ASB3
Target Full Name
Ankyrin repeat and SOCS box protein 3
Target Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B.
Target Protein Families
Ankyrin SOCS box (ASB) family
Target Synonyms
ASB3Ankyrin repeat and SOCS box protein 3; ASB-3
Target Background
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.
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