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| Cat.No | ACP15989 | Target Name | ANKRD11 |
|---|---|---|---|
| Target Synonyms | ANKRD11; ANCO1Ankyrin repeat domain-containing protein 11; Ankyrin repeat-containing cofactor 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UB99 |
|---|
Uniprot Id
Q6UB99
Target Species
Human
Target Name
ANKRD11
Target Full Name
Ankyrin repeat domain-containing protein 11
Target Function
Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells. May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Has a role in proliferation and development of cortical neural precursors. May also regulate bone homeostasis.
Target Involvement
KBG syndrome (KBGS)
Target Subcellular Location
Nucleus.
Target Synonyms
ANKRD11; ANCO1Ankyrin repeat domain-containing protein 11; Ankyrin repeat-containing cofactor 1
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