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| Cat.No | ACP15539 | Target Name | ANKRD13B |
|---|---|---|---|
| Target Synonyms | ANKRD13BAnkyrin repeat domain-containing protein 13B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-626 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86YJ7 |
|---|
Uniprot Id
Q86YJ7
Target Species
Human
Target Name
ANKRD13B
Target Full Name
Ankyrin repeat domain-containing protein 13B
Target Function
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Target Subcellular Location
Cell membrane. Late endosome. Early endosome. Note=Interaction with EGFR may enhance association with the cell membrane.
Target Synonyms
ANKRD13BAnkyrin repeat domain-containing protein 13B
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