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| Cat.No | ACP16465 | Target Name | ANKRD16 |
|---|---|---|---|
| Target Synonyms | Ankrd16; Ankyrin repeat domain 16; Ankyrin repeat domain-containing protein 16; ANR16_HUMAN; DKFZP434N1511 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-361 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P6B7 |
|---|
Uniprot Id
Q6P6B7
Target Species
Human
Target Name
ANKRD16
Target Full Name
Ankyrin repeat domain-containing protein 16
Target Function
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Synonyms
Ankrd16; Ankyrin repeat domain 16; Ankyrin repeat domain-containing protein 16; ANR16_HUMAN; DKFZP434N1511
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