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| Cat.No | ACP12651 | Target Name | ANKRD9 |
|---|---|---|---|
| Target Synonyms | ANKRD9Ankyrin repeat domain-containing protein 9 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-317 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96BM1 |
|---|
Uniprot Id
Q96BM1
Target Species
Human
Target Name
ANKRD9
Target Full Name
Ankyrin repeat domain-containing protein 9
Target Function
Substrate receptor subunit of a cullin-RING superfamily E3 ligase complex (CUL5-based E3 ubiquitin ligase complex) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Depending of the metabolic state of the cell, promotes the proteasomal degradation of IMPDH2, the rate-limiting enzyme in GTP biosynthesis or protects IMPDH2 by stabilizing IMPDH2 filaments assembly. Implicated in different cellular processes, like copper homeostasis and cell proliferation.
Target Subcellular Location
Cytoplasmic vesicle. Cytoplasm, cytosol.
Target Synonyms
ANKRD9Ankyrin repeat domain-containing protein 9
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