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| Cat.No | ACP05754 | Target Name | ANO3 |
|---|---|---|---|
| Target Synonyms | ANO3; C11orf25; TMEM16C; GENX-3947Anoctamin-3; Transmembrane protein 16C | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BYT9 |
|---|
Uniprot Id
Q9BYT9
Target Species
Human
Target Name
ANO3
Target Full Name
Anoctamin-3
Target Function
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity. Does not exhibit calcium-activated chloride channel (CaCC) activity.
Target Involvement
Dystonia 24 (DYT24)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Anoctamin family
Target Tissue Specificity
Highly expressed in the forebrain striatum.
Target Synonyms
ANO3; C11orf25; TMEM16C; GENX-3947Anoctamin-3; Transmembrane protein 16C
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