Recombinant Human AP-3 complex subunit beta-2 (AP3B2), Truncated

Cat.No	ACP17976	Target Name	AP3B2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP17976

Target Name

AP3B2

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q13367

Background Information

Uniprot Id

Q13367
Target Species

Human
Target Name

AP3B2
Target Full Name

AP-3 complex subunit beta-2
Target Function

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals
Target Involvement

Epileptic encephalopathy, early infantile, 48 (EIEE48)
Target Subcellular Location

Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus.
Target Protein Families

Adaptor complexes large subunit family
Target Tissue Specificity

Isoform 1 expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deepe
Target Research Area

Neuroscience
Target Synonyms

Adapter-related protein complex 3 subunit beta-2; Adaptor protein complex AP-3 subunit beta-2; Adaptor related protein complex 3 beta 2 subunit; AP 3 complex subunit beta 2; AP-3 complex subunit beta-2; AP3B2; AP3B2_HUMAN; beta NAP; Beta-3B-adaptin; Beta3B adaptin; Beta3b; Clathrin assembly protein complex 3 beta 2 large chain; Clathrin assembly protein complex 3 beta-2 large chain; NAPTB; Neuron specific vesicle coat protein and cerebellar degeneration antigen; Neuron-specific vesicle coat protein beta-NAP; Neuronal adaptin like protein beta subunit

Recombinant Human AP-3 complex subunit beta-2 (AP3B2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human AP-3 complex subunit beta-2 (AP3B2), Truncated Now

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