Recombinant Human AP-3 complex subunit delta-1 (AP3D1), Truncated

Cat.No	ACP21565	Target Name	AP3D1
Target Synonyms	Adapter-related protein complex 3 subunit delta-1; adaptor-related protein complex 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP21565

Target Name

AP3D1

Target Synonyms

Adapter-related protein complex 3 subunit delta-1; adaptor-related protein complex 3

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	O14617

Background Information

Uniprot Id

O14617
Target Species

Human
Target Name

AP3D1
Target Full Name

AP-3 complex subunit delta-1
Target Function

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Target Involvement

Hermansky-Pudlak syndrome 10 (HPS10)
Target Subcellular Location

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families

Adaptor complexes large subunit family
Target Tissue Specificity

Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
Target Synonyms

Adapter-related protein complex 3 subunit delta-1; adaptor-related protein complex 3, delta 1 subunit; ADTD; AP 3 complex delta subunit; AP-3 complex subunit delta; AP-3 complex subunit delta-1; ap3d1; AP3D1_HUMAN; Delta 1 subunit of adaptor-related protein complex 3; Delta Adaptin; Delta-adaptin; hBLVR; Subunit of putative vesicle coat adaptor complex AP 3
Target Background

The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome.

Recombinant Human AP-3 complex subunit delta-1 (AP3D1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human AP-3 complex subunit delta-1 (AP3D1), Truncated Now

Related Products