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| Cat.No | ACP03424 | Target Name | ADAP1 |
|---|---|---|---|
| Target Synonyms | ADAP1; CENTA1Arf-GAP with dual PH domain-containing protein 1; Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating protein PM25 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-374aa |
| Mol Weight | 70.4kDa | Protein Length | Full Length of BC033747 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75689 |
|---|
Uniprot Id
O75689
Target Species
Human
Target Name
ADAP1
Target Full Name
Arf-GAP with dual PH domain-containing protein 1
Target Function
GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Target Subcellular Location
Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.
Target Tissue Specificity
Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Target Research Area
Microbiology
Target Synonyms
ADAP1; CENTA1Arf-GAP with dual PH domain-containing protein 1; Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating protein PM25
Target Background
Enables GTPase activator activity. Involved in regulation of GTPase activity. Located in cytosol; nucleus; and plasma membrane.
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