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| Cat.No | ACP12693 | Target Name | ARAP2 |
|---|---|---|---|
| Target Synonyms | ARAP2; CENTD1; KIAA0580Arf-GAP with Rho-GAP domain; ANK repeat and PH domain-containing protein 2; Centaurin-delta-1; Cnt-d1; Protein PARX | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WZ64 |
|---|
Uniprot Id
Q8WZ64
Target Species
Human
Target Name
ARAP2
Target Full Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
Target Function
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes.
Target Synonyms
ARAP2; CENTD1; KIAA0580Arf-GAP with Rho-GAP domain; ANK repeat and PH domain-containing protein 2; Centaurin-delta-1; Cnt-d1; Protein PARX
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