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| Cat.No | ACP22801 | Target Name | ARFIP2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-341 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P53365 |
|---|
Uniprot Id
P53365
Target Species
Human
Target Name
ARFIP2
Target Full Name
Arfaptin-2
Target Function
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Target Synonyms
ADP ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; ARFIP2; ARFP2_HUMAN; FLJ18046; FLJ18697; FLJ99239; Partner of RAC1; POR1; Protein POR1
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