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| Cat.No | ACP21016 | Target Name | ATE1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-518 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95260 |
|---|
Uniprot Id
O95260
Target Species
Human
Target Name
ATE1
Target Full Name
Arginyl-tRNA--protein transferase 1
Target Function
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.
Target Subcellular Location
[Isoform ATE1-1]: Nucleus. Cytoplasm.; [Isoform ATE1-2]: Cytoplasm.
Target Protein Families
R-transferase family
Target Synonyms
AI225793; Arginine tRNA protein transferase 1; Arginine-tRNA--protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; Ate1; ATE1_HUMAN; AW547406; EC 2.3.2.8; MGC26724; OTTHUMP00000020637; OTTHUMP00000058665; R transferase 1; R-transferase 1
Target Background
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants.
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