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Recombinant Human Arrestin domain-containing protein 1 (ARRDC1)

ACP13110

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13110 Target NameARRDC1
Target SynonymsARRD1_HUMAN; ARRDC 1; ARRDC1; Arrestin domain containing 1; Arrestin domain containing protein 1; Arrestin domain-containing protein 1; MGC40555; OTTHUMP00000022707; OTTHUMP00000022709; RP11-48C7.5FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-433
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N5I2
Background Information
  • Uniprot Id

    Q8N5I2

  • Target Species

    Human

  • Target Name

    ARRDC1

  • Target Full Name

    Arrestin domain-containing protein 1

  • Target Function

    Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles. More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles. By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway.

  • Target Subcellular Location

    Cell membrane.

  • Target Protein Families

    Arrestin family

  • Target Synonyms

    ARRD1_HUMAN; ARRDC 1; ARRDC1; Arrestin domain containing 1; Arrestin domain containing protein 1; Arrestin domain-containing protein 1; MGC40555; OTTHUMP00000022707; OTTHUMP00000022709; RP11-48C7.5

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