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| Cat.No | ACP24082 | Target Name | ARSA |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 19-507 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P15289 |
|---|
Uniprot Id
P15289
Target Species
Human
Target Name
ARSA
Target Full Name
Arylsulfatase A
Target Function
Hydrolyzes cerebroside sulfate.
Target Involvement
Metachromatic leukodystrophy (MLD); Multiple sulfatase deficiency (MSD)
Target Subcellular Location
Endoplasmic reticulum. Lysosome.
Target Protein Families
Sulfatase family
Target Synonyms
arsA; ARSA_HUMAN; arylsulfatase A; Arylsulfatase A component C; As 2; AS A; As2; ASA; AW212749; C230037L18Rik; Cerebroside-sulfatase; metachromatic leucodystrophy; MGC125207; MLD; OTTHUMP00000196546; OTTHUMP00000196548; TISP73
Target Background
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
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