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| Cat.No | ACP05367 | Target Name | ASTN2 |
|---|---|---|---|
| Target Synonyms | Astn2; ASTN2_HUMAN; Astrotactin 2; Astrotactin-2; bA264C15.1; bA67K19.1; KIAA0634 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75129 |
|---|
Uniprot Id
O75129
Target Species
Human
Target Name
ASTN2
Target Full Name
Astrotactin-2
Target Function
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1. Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6).
Target Subcellular Location
Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, cell cortex. Early endosome. Late endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle.
Target Protein Families
Astrotactin family
Target Synonyms
Astn2; ASTN2_HUMAN; Astrotactin 2; Astrotactin-2; bA264C15.1; bA67K19.1; KIAA0634
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