Home Products Recombinant Human Ataxin-7-like protein 3 (ATXN7L3)

Recombinant Human Ataxin-7-like protein 3 (ATXN7L3)

ACP18459

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Specifications

Cat.No	ACP18459	Target Name	ATXN7L3
Target Synonyms	AT7L3_HUMAN; Ataxin 7 like 3; Ataxin 7 like protein 3; Ataxin-7-like protein 3; atxn7l3; SAGA associated factor 11 homolog; SAGA-associated factor 11 homolog	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-347
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14CW9

Background Information

Uniprot Id

Q14CW9
Target Species

Human
Target Name

ATXN7L3
Target Full Name

Ataxin-7-like protein 3
Target Function

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
Target Subcellular Location

Nucleus.
Target Protein Families

SGF11 family
Target Research Area

Cell Biology
Target Synonyms

AT7L3_HUMAN; Ataxin 7 like 3; Ataxin 7 like protein 3; Ataxin-7-like protein 3; atxn7l3; SAGA associated factor 11 homolog; SAGA-associated factor 11 homolog

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Recombinant Human Ataxin-7-like protein 3 (ATXN7L3)

Specifications

Immunogen Information

Inquire Recombinant Human Ataxin-7-like protein 3 (ATXN7L3) Now

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