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Recombinant Human ATM interactor (ATMIN), Truncated

ACP21223

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21223 Target NameATMIN
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO43313
Background Information
  • Uniprot Id

    O43313

  • Target Species

    Human

  • Target Name

    ATMIN

  • Target Full Name

    ATM interactor

  • Target Function

    Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.

  • Target Subcellular Location

    Nucleus. Note=Nuclear, in discrete foci during G1 phase.

  • Target Tissue Specificity

    Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.

  • Target Synonyms

    ASCIZ; ATM INteracting protein; ATM interactor; ATM substrate CHK2-interacting zinc finger protein; ATM/ATR substrate CHEK2 interacting zinc finger protein; ATM/ATR Substrate Chk2 Interacting Zn++ finger protein; ATM/ATR substrate Chk2 interacting Zn2+ finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATMIN; ATMIN_HUMAN; DKFZp779K1455; FLJ76795; KIAA0431; Zinc finger protein 822; ZNF 822; ZNF822

  • Target Background

    Enables dynein complex binding activity. Involved in positive regulation of transcription, DNA-templated. Located in nuclear body.

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