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| Cat.No | ACP21223 | Target Name | ATMIN |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43313 |
|---|
Uniprot Id
O43313
Target Species
Human
Target Name
ATMIN
Target Full Name
ATM interactor
Target Function
Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.
Target Subcellular Location
Nucleus. Note=Nuclear, in discrete foci during G1 phase.
Target Tissue Specificity
Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
Target Synonyms
ASCIZ; ATM INteracting protein; ATM interactor; ATM substrate CHK2-interacting zinc finger protein; ATM/ATR substrate CHEK2 interacting zinc finger protein; ATM/ATR Substrate Chk2 Interacting Zn++ finger protein; ATM/ATR substrate Chk2 interacting Zn2+ finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATMIN; ATMIN_HUMAN; DKFZp779K1455; FLJ76795; KIAA0431; Zinc finger protein 822; ZNF 822; ZNF822
Target Background
Enables dynein complex binding activity. Involved in positive regulation of transcription, DNA-templated. Located in nuclear body.
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