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Recombinant Human ATP-binding cassette sub-family A member 1 (ABCA1), Truncated

ACP05349

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Specifications

Cat.No	ACP05349	Target Name	ABCA1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95477

Background Information

Uniprot Id

O95477
Target Species

Human
Target Name

ABCA1
Target Full Name

Phospholipid-transporting ATPase ABCA1
Target Function

Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Thereby, participates in phospholipid transfer to apoliproteins to form nascent high density lipoproteins/HDLs. Transports preferentially phosphatidylcholine over phosphatidylserine. May play a similar role in the efflux of intracellular cholesterol to apoliproteins and the formation of nascent high density lipoproteins/HDLs.
Target Involvement

High density lipoprotein deficiency 1 (HDLD1); High density lipoprotein deficiency 2 (HDLD2)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Endosome.
Target Protein Families

ABC transporter superfamily, ABCA family
Target Tissue Specificity

Widely expressed, but most abundant in macrophages.
Target Synonyms

ABC 1; ABC Transporter 1; ABC-1; ABC1; ABCA 1; ABCA1; ABCA1_HUMAN; ATP binding Cassette 1; ATP binding cassette sub family A ABC1 member 1; ATP binding cassette sub family A member 1; ATP binding Cassette Transporter 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; CERP; Cholesterol efflux regulatory protein; FLJ14958; HDLDT1; Membrane bound; MGC164864; MGC165011; TD; TGD

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Recombinant Human ATP-binding cassette sub-family A member 1 (ABCA1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human ATP-binding cassette sub-family A member 1 (ABCA1), Truncated Now

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