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Recombinant Human ATP-binding cassette sub-family D member 3 (ABCD3), Truncated

ACP07049

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07049 Target NameABCD3
Target SynonymsABCD3; PMP70; PXMP1; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP28288
Background Information
  • Uniprot Id

    P28288

  • Target Species

    Human

  • Target Name

    ABCD3

  • Target Full Name

    ATP-binding cassette sub-family D member 3

  • Target Function

    Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation

  • Target Involvement

    Congenital bile acid synthesis defect 5 (CBAS5)

  • Target Subcellular Location

    Peroxisome membrane; Multi-pass membrane protein.

  • Target Protein Families

    ABC transporter superfamily, ABCD family, Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily

  • Target Synonyms

    ABCD3; PMP70; PXMP1; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70

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