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| Cat.No | ACP07049 | Target Name | ABCD3 |
|---|---|---|---|
| Target Synonyms | ABCD3; PMP70; PXMP1; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P28288 |
|---|
Uniprot Id
P28288
Target Species
Human
Target Name
ABCD3
Target Full Name
ATP-binding cassette sub-family D member 3
Target Function
Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation
Target Involvement
Congenital bile acid synthesis defect 5 (CBAS5)
Target Subcellular Location
Peroxisome membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCD family, Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily
Target Synonyms
ABCD3; PMP70; PXMP1; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70
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