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Recombinant Human ATP-dependent DNA helicase Q4 (RECQL4), Truncated

ACP20858

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20858 Target NameRECQL4
Target SynonymsATP dependent DNA helicase Q4; ATP-dependent DNA helicase Q4; DNA helicase; DNA helicase, RecQ like type 4; RECQ 4; RECQ L4; RecQ protein 4; RecQ protein like 4; RecQ protein-like 4; RecQ-like type 4; RecQ4; RECQ4_HUMAN; RECQL 4; RECQL4; RTSFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO94761
Background Information
  • Uniprot Id

    O94761

  • Target Species

    Human

  • Target Name

    RECQL4

  • Target Full Name

    ATP-dependent DNA helicase Q4

  • Target Function

    DNA-dependent ATPase. May modulate chromosome segregation.

  • Target Involvement

    Rothmund-Thomson syndrome (RTS); RAPADILINO syndrome (RAPADILINOS); Baller-Gerold syndrome (BGS)

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    Helicase family, RecQ subfamily

  • Target Tissue Specificity

    Ubiquitously expressed, with highest levels in thymus and testis.

  • Target Synonyms

    ATP dependent DNA helicase Q4; ATP-dependent DNA helicase Q4; DNA helicase; DNA helicase, RecQ like type 4; RECQ 4; RECQ L4; RecQ protein 4; RecQ protein like 4; RecQ protein-like 4; RecQ-like type 4; RecQ4; RECQ4_HUMAN; RECQL 4; RECQL4; RTS

  • Target Background

    The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.

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