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| Cat.No | ACP00883 | Target Name | ECRG4 |
|---|---|---|---|
| Target Synonyms | Esophageal cancer-related gene 4 protein;ECRG4 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 71-132aa |
| Mol Weight | 12.9 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H1Z8 |
|---|
Uniprot Id
Q9H1Z8
Target Species
Human
Target Name
ECRG4
Target Full Name
Augurin
Target Function
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.
Target Subcellular Location
Secreted. Cytoplasm. Apical cell membrane.
Target Protein Families
Augurin family
Target Tissue Specificity
Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level).
Target Research Area
Cancer
Target Synonyms
AUGN_HUMAN; Augurin; C2orf40; Esophageal cancer-related gene 4 protein
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