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Recombinant Human Bcl-2-modifying factor (BMF)

ACP13180

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Specifications

Cat.No	ACP13180	Target Name	BMF
Target Synonyms	Bcl 2 modifying factor; Bcl-2-modifying factor; Bcl2 modifying factor; Bmf; BMF_HUMAN; FLJ00065	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-184aa
Protein Length	Full Length of BC069505	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96LC9

Background Information

Uniprot Id

Q96LC9
Target Species

Human
Target Name

BMF
Target Full Name

Bcl-2-modifying factor
Target Function

May play a role in apoptosis. Isoform 1 seems to be the main initiator.
Target Protein Families

Bcl-2 family
Target Tissue Specificity

Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.
Target Research Area

Cell Biology
Target Synonyms

Bcl 2 modifying factor; Bcl-2-modifying factor; Bcl2 modifying factor; Bmf; BMF_HUMAN; FLJ00065
Target Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Recombinant Human Bcl-2-modifying factor (BMF)

Specifications

Immunogen Information

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