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| Cat.No | ACP16085 | Target Name | B3GLCT |
|---|---|---|---|
| Target Synonyms | 3-glucosyltransferase; Beta3Glc-T; EC 2.4.1.-; Beta 3-glucosyltransferase; Beta-3-glycosyltransferase-like, B3GLCT; B3GALTL; B3GTLBeta-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6Y288 |
|---|
Uniprot Id
Q6Y288
Target Species
Human
Target Name
B3GLCT
Target Full Name
Beta-1,3-glucosyltransferase
Target Function
O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
Target Involvement
Peters-plus syndrome (PPLS)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 31 family
Target Tissue Specificity
Widely expressed, with highest levels in testis and uterus.
Target Synonyms
B3GLCT; B3GALTL; B3GTLBeta-1,3-glucosyltransferase; Beta3Glc-T; EC 2.4.1.-; Beta 3-glucosyltransferase; Beta-3-glycosyltransferase-like
Target Background
The protein encoded by this gene is a beta-1, 3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).
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