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| Cat.No | ACP02161 | Target Name | ADRB3 |
|---|---|---|---|
| Target Synonyms | Beta-3 adrenoreceptor;Beta-3 adrenoceptor | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-408aa |
| Mol Weight | 49.6 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P13945 |
|---|
Uniprot Id
P13945
Target Species
Human
Target Name
ADRB3
Target Full Name
Beta-3 adrenergic receptor
Target Function
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamily
Target Tissue Specificity
Expressed mainly in adipose tissues.
Target Research Area
Cardiovascular
Target Synonyms
ADRB3; ADRB3R; B3AR; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor
Target Background
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.
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