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| Cat.No | ACP12274 | Target Name | NDST4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H3R1 |
|---|
Uniprot Id
Q9H3R1
Target Species
Human
Target Name
NDST4
Target Full Name
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
Target Function
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 1 family, NDST subfamily
Target Synonyms
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 ; BSST4; Glucosaminyl N-deacetylase/N-sulfotransferase 4; Heparan sulfate N-sulfotransferase 4; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; N-heparan sulfate sulfotransferase 4; N-HSST 4; NDST-4; Ndst4; NDST4_HUMAN; NHSST 4
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