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Delve into the world of signal transduction with our premium Recombinant Human BGN protein, an essential component of the extracellular matrix. Biglycan, also known as bone/cartilage proteoglycan I or PG-S1, is a small leucine-rich proteoglycan that plays a pivotal role in regulating cell adhesion, growth, and differentiation. Its involvement in key cellular processes and interactions makes it a valuable protein for researchers exploring signal transduction pathways and related mechanisms. Our Recombinant Human BGN protein is expressed in E. coli, ensuring a high-quality and robust product. It spans the full length of the mature protein, covering the 38-368aa region, retaining the essential functional domains for your experimental needs. The N-terminal 10xHis-SUMO tag and C-terminal Myc tag facilitate efficient protein purification and detection, simplifying your workflow. With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human BGN protein is provided as a lyophilized powder, offering you a reliable and consistent tool for your signal transduction research projects.
Delve into the world of signal transduction with our premium Recombinant Human BGN protein, an essential component of the extracellular matrix. Biglycan, also known as bone/cartilage proteoglycan I or PG-S1, is a small leucine-rich proteoglycan that plays a pivotal role in regulating cell adhesion, growth, and differentiation. Its involvement in key cellular processes and interactions makes it a valuable protein for researchers exploring signal transduction pathways and related mechanisms.
Our Recombinant Human BGN protein is expressed in E. coli, ensuring a high-quality and robust product. It spans the full length of the mature protein, covering the 38-368aa region, retaining the essential functional domains for your experimental needs. The N-terminal 10xHis-SUMO tag and C-terminal Myc tag facilitate efficient protein purification and detection, simplifying your workflow. With a purity greater than 90% as determined by SDS-PAGE, our Recombinant Human BGN protein is provided as a lyophilized powder, offering you a reliable and consistent tool for your signal transduction research projects.
| Cat.No | ACP02341 | Target Name | BGN |
|---|---|---|---|
| Target Synonyms | BGN; Biglycan; Biglycan proteoglycan; Bone/cartilage proteoglycan I; Dermatan sulphate proteoglycan I; DSPG1 ; PG S1; PG-S1; PGI; PGS1_HUMAN; SEMDX; SLRR1A; Small leucine rich protein 1A | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 38-368aa |
| Mol Weight | 57.2kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P21810 |
|---|
Uniprot Id
P21810
Target Species
Human
Target Name
BGN
Target Full Name
Biglycan
Target Function
May be involved in collagen fiber assembly.
Target Involvement
Meester-Loeys syndrome (MRLS); Spondyloepimetaphyseal dysplasia, X-linked (SEMDX)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class I subfamily
Target Tissue Specificity
Found in several connective tissues, especially in articular cartilages.
Target Research Area
Signal Transduction
Target Synonyms
BGN; Biglycan; Biglycan proteoglycan; Bone/cartilage proteoglycan I; Dermatan sulphate proteoglycan I; DSPG1 ; PG S1; PG-S1; PGI; PGS1_HUMAN; SEMDX; SLRR1A; Small leucine rich protein 1A
Target Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.
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