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| Cat.No | ACP23407 | Target Name | BTD |
|---|---|---|---|
| Target Synonyms | Biotinase; Biotinidase; Btd; BTD_HUMAN; EC 3.5.1.12 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 42-543 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P43251 |
|---|
Uniprot Id
P43251
Target Species
Human
Target Name
BTD
Target Full Name
Biotinidase
Target Function
Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
Target Involvement
Biotinidase deficiency (BTD deficiency)
Target Subcellular Location
Secreted, extracellular space.
Target Protein Families
Carbon-nitrogen hydrolase superfamily, BTD/VNN family
Target Research Area
Metabolism
Target Synonyms
Biotinase; Biotinidase; Btd; BTD_HUMAN; EC 3.5.1.12
Target Background
The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.
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