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| Cat.No | ACP14818 | Target Name | BAHD1 |
|---|---|---|---|
| Target Synonyms | BAHD1; KIAA0945Bromo adjacent homology domain-containing 1 protein; BAH domain-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-780 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TBE0 |
|---|
Uniprot Id
Q8TBE0
Target Species
Human
Target Name
BAHD1
Target Full Name
Bromo adjacent homology domain-containing 1 protein
Target Function
Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon-stimulated genes, including IFNL1, IFNL2 and IFNL3.
Target Subcellular Location
Nucleus. Chromosome. Note=Localizes to heterochromatin and inactive X chromosome. Colocalizes with histone H3 trimethylated at 'Lys-27' (H3K27me3).
Target Synonyms
BAHD1; KIAA0945Bromo adjacent homology domain-containing 1 protein; BAH domain-containing protein 1
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