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| Cat.No | ACP10095 | Target Name | BRPF3 |
|---|---|---|---|
| Target Synonyms | BRPF3; KIAA1286Bromodomain and PHD finger-containing protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9ULD4 |
|---|
Uniprot Id
Q9ULD4
Target Species
Human
Target Name
BRPF3
Target Full Name
Bromodomain and PHD finger-containing protein 3
Target Function
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Target Subcellular Location
Nucleus.
Target Synonyms
BRPF3; KIAA1286Bromodomain and PHD finger-containing protein 3
Target Background
Predicted to enable histone binding activity. Involved in histone H3-K14 acetylation and positive regulation of DNA replication. Part of MOZ/MORF histone acetyltransferase complex.
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