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| Cat.No | ACP19812 | Target Name | BTBD18 |
|---|---|---|---|
| Target Synonyms | BTBD18BTB/POZ domain-containing protein 18 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-712 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | B2RXH4 |
|---|
Uniprot Id
B2RXH4
Target Species
Human
Target Name
BTBD18
Target Full Name
BTB/POZ domain-containing protein 18
Target Function
Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene.
Target Subcellular Location
Nucleus.
Target Synonyms
BTBD18BTB/POZ domain-containing protein 18
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