Recombinant Human Butyrophilin subfamily 2 member A1 (BTN2A1), Truncated

Uniprot Id

Q7KYR7

Target Species

Human

Target Name

BTN2A1

Target Full Name

Butyrophilin subfamily 2 member A1

Target Subcellular Location

Membrane; Single-pass type I membrane protein.

Target Protein Families

Immunoglobulin superfamily, BTN/MOG family

Target Tissue Specificity

Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.

Target Research Area

Signal Transduction

Target Synonyms

BK14H9.1; BT2.1; BT2A1_HUMAN; BTF1; BTN2A1; Butyrophilin BTF1; Butyrophilin subfamily 2 member A1; CTA-14H9.1; DJ3E1.1

Target Background

This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.