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Recombinant Human Butyrophilin subfamily 3 member A3 (BTN3A3)

ACP09158

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP09158 Target NameBTN3A3
Target SynonymsBT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range30-248
Protein LengthExtracellular DomainPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO00478
Background Information
  • Uniprot Id

    O00478

  • Target Species

    Human

  • Target Name

    BTN3A3

  • Target Full Name

    Butyrophilin subfamily 3 member A3

  • Target Function

    Plays a role in T-cell responses in the adaptive immune response.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Immunoglobulin superfamily, BTN/MOG family

  • Target Tissue Specificity

    Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    BT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3

  • Target Background

    The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).

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