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| Cat.No | ACP09158 | Target Name | BTN3A3 |
|---|---|---|---|
| Target Synonyms | BT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 30-248 |
| Protein Length | Extracellular Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00478 |
|---|
Uniprot Id
O00478
Target Species
Human
Target Name
BTN3A3
Target Full Name
Butyrophilin subfamily 3 member A3
Target Function
Plays a role in T-cell responses in the adaptive immune response.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, BTN/MOG family
Target Tissue Specificity
Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.
Target Research Area
Cardiovascular
Target Synonyms
BT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3
Target Background
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).
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