Recombinant Human C-C motif chemokine 23 (CCL23)

Uniprot Id

P55773

Target Species

Human

Target Name

CCL23

Target Full Name

C-C motif chemokine 23

Target Function

Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.

Target Subcellular Location

Secreted.

Target Protein Families

Intercrine beta (chemokine CC) family

Target Tissue Specificity

High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CC

Target Synonyms

C C motif chemokine ligand 23; C-C motif chemokine 23; C6 beta chemokine ; CCL 23; CCL23; CCL23(30-99); CCL23_HUMAN; Chemokine (C C motif) ligand 23; Chemokine CC motif ligand 23; ck beta 8; CK-beta-8; CKB 8 ; CKB-8; Ckb-8-1; CKB8 ; Hmrp-2a; Macrophage inflammatory protein 3; MIP 3; MIP-3; MIP3; MPIF 1; MPIF-1; MPIF1; Myeloid progenitor inhibitory factor 1; OTTHUMP00000163948 ; SCYA 23; SCYA23; Small inducible cytokine A 23; Small inducible cytokine subfamily A (Cys-Cys); member 23 ; Small inducible cytokine subfamily A; member 23; Small-inducible cytokine A23