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| Cat.No | ACP00372 | Target Name | CLEC9A |
|---|---|---|---|
| Target Synonyms | CD370 | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Expression Range | 57-241aa |
| Mol Weight | 50.4 kDa | Protein Length | Partial |
| Purity | Greater than 95% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UXN8 |
|---|
Uniprot Id
Q6UXN8
Target Species
Human
Target Name
CLEC9A
Target Full Name
C-type lectin domain family 9 member A
Target Function
Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Tissue Specificity
In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.
Target Research Area
Immunology
Target Synonyms
C type lectin domain family 9; member A; C-type lectin domain family 9 member A; CLC9A_HUMAN; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341
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