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Recombinant Human Calmodulin-like protein 3 (CALML3)

The region for expressing recombinant Human CALML3 contains amino acids 1-149. The calculated molecular weight for this CALML3 protein is 43.9 kDa. This protein is generated in a e.coli-based system. The N-terminal GST tag was fused into the coding gene segment of CALML3, making it easier to detect and purify the CALML3 recombinant protein in the later stages of expression and purification.One of the primary research areas for Calmodulin-like protein 3 (CALML3) is cellular signal transduction and regulation. CALML3 serves as a mediator and modulator of calcium signals within cells, participating in the regulation of various cellular processes, including cell proliferation, differentiation, and apoptosis. In cancer research, the expression of CALML3 is associated with the occurrence and development of various tumors. Scientists are delving into understanding the specific functions of CALML3 in cancer cells to identify new approaches for cancer treatment. Additionally, CALML3 is implicated in research related to the cardiovascular system. Its regulatory role in cardiac muscle cells may play a crucial role in the onset of cardiovascular diseases. Relevant studies contribute to revealing the precise functions of CALML3 in cardiovascular health and disease.

ACP03586

The region for expressing recombinant Human CALML3 contains amino acids 1-149. The calculated molecular weight for this CALML3 protein is 43.9 kDa. This protein is generated in a e.coli-based system. The N-terminal GST tag was fused into the coding gene segment of CALML3, making it easier to detect and purify the CALML3 recombinant protein in the later stages of expression and purification.One of the primary research areas for Calmodulin-like protein 3 (CALML3) is cellular signal transduction and regulation. CALML3 serves as a mediator and modulator of calcium signals within cells, participating in the regulation of various cellular processes, including cell proliferation, differentiation, and apoptosis. In cancer research, the expression of CALML3 is associated with the occurrence and development of various tumors. Scientists are delving into understanding the specific functions of CALML3 in cancer cells to identify new approaches for cancer treatment. Additionally, CALML3 is implicated in research related to the cardiovascular system. Its regulatory role in cardiac muscle cells may play a crucial role in the onset of cardiovascular diseases. Relevant studies contribute to revealing the precise functions of CALML3 in cardiovascular health and disease.

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Specifications


Cat.No ACP03586 Target NameCALML3
Target SynonymsCALL3_HUMAN; CALML3; Calmodulin like 3; Calmodulin related protein NB 1; Calmodulin-like protein 3; Calmodulin-related protein NB-1; CaM like protein; CaM-like protein; CLP; OTTHUMP00000019004FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range1-149aa
Mol Weight43.9kDaProtein LengthFull length
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP27482
Background Information
  • Uniprot Id

    P27482

  • Target Species

    Human

  • Target Name

    CALML3

  • Target Full Name

    Calmodulin-like protein 3

  • Target Function

    May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates.

  • Target Protein Families

    Calmodulin family

  • Target Tissue Specificity

    Expressed in normal mammary, prostate, cervical, and epidermal tissues. It is greatly reduced or undetectable in transformed cells.

  • Target Research Area

    Tags & Cell Markers

  • Target Synonyms

    CALL3_HUMAN; CALML3; Calmodulin like 3; Calmodulin related protein NB 1; Calmodulin-like protein 3; Calmodulin-related protein NB-1; CaM like protein; CaM-like protein; CLP; OTTHUMP00000019004

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