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| Cat.No | ACP09657 | Target Name | CAPN7 |
|---|---|---|---|
| Target Synonyms | CAPN7; PALBHCalpain-7; EC 3.4.22.-; PalB homolog; PalBH | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y6W3 |
|---|
Uniprot Id
Q9Y6W3
Target Species
Human
Target Name
CAPN7
Target Full Name
Calpain-7
Target Function
Calcium-regulated non-lysosomal thiol-protease.
Target Subcellular Location
Nucleus.
Target Protein Families
Peptidase C2 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
CAPN7; PALBHCalpain-7; EC 3.4.22.-; PalB homolog; PalBH
Target Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
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