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Recombinant Human Carbonyl reductase [NADPH] 3 (CBR3)

ACP20871

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20871 Target NameCBR3
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-277Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75828
Background Information
  • Uniprot Id

    O75828

  • Target Species

    Human

  • Target Name

    CBR3

  • Target Full Name

    Carbonyl reductase [NADPH] 3

  • Target Function

    Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family

  • Target Tissue Specificity

    Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.

  • Target Synonyms

    Carbonyl reductase (NADPH) 3; Carbonyl reductase (NADPH) 3 EC 1.1.1.184; Carbonyl reductase [NADPH] 3; Carbonyl reductase 3; CBR 3; CBR3; CBR3_HUMAN; EC 1.1.1.184; Epididymis secretory protein Li 25; hCBR3; HEL S 25; NADPH dependent carbonyl reductase 3; NADPH-dependent carbonyl reductase 3; SDR21C2; Short chain dehydrogenase/reductase family 21C member 2

  • Target Background

    Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

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