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Recombinant Human Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2)

ACP21738

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Specifications

Cat.No	ACP21738	Target Name	CTDSP2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-271	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O14595

Background Information

Uniprot Id

O14595
Target Species

Human
Target Name

CTDSP2
Target Full Name

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
Target Function

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.
Target Synonyms

Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma 4; conserved gene amplified in osteosarcoma; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting factor 2; NLI-interacting factor 2; Nuclear LIM interactor interacting factor 2; Nuclear LIM interactor-interacting factor 2; OS4; Protein OS 4; Protein OS-4; PSR2; SCP2; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2

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Recombinant Human Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2)

Specifications

Immunogen Information

Inquire Recombinant Human Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) Now

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