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| Cat.No | ACP13519 | Target Name | CMBL |
|---|---|---|---|
| Target Synonyms | Carboxymethylenebutenolidase homolog (Pseudomonas); Carboxymethylenebutenolidase homolog; cmbl; CMBL_HUMAN; FLJ23617 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-245 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96DG6 |
|---|
Uniprot Id
Q96DG6
Target Species
Human
Target Name
CMBL
Target Full Name
Carboxymethylenebutenolidase homolog
Target Function
Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
Dienelactone hydrolase family
Target Tissue Specificity
Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
Target Synonyms
Carboxymethylenebutenolidase homolog (Pseudomonas); Carboxymethylenebutenolidase homolog; cmbl; CMBL_HUMAN; FLJ23617
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