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| Cat.No | ACP24356 | Target Name | CPM |
|---|---|---|---|
| Target Synonyms | Carboxypeptidase M; CBPM_HUMAN; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 18-423 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P14384 |
|---|
Uniprot Id
P14384
Target Species
Human
Target Name
CPM
Target Full Name
Carboxypeptidase M
Target Function
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Peptidase M14 family
Target Synonyms
Carboxypeptidase M; CBPM_HUMAN; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B
Target Background
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
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