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Recombinant Human Carboxypeptidase M (CPM)

ACP24356

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24356 Target NameCPM
Target SynonymsCarboxypeptidase M; CBPM_HUMAN; CPM; Renal carboxypeptidase; Urinary carboxypeptidase BFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range18-423
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP14384
Background Information
  • Uniprot Id

    P14384

  • Target Species

    Human

  • Target Name

    CPM

  • Target Full Name

    Carboxypeptidase M

  • Target Function

    Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    Peptidase M14 family

  • Target Synonyms

    Carboxypeptidase M; CBPM_HUMAN; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B

  • Target Background

    The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

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