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Recombinant Human Cbp/p300-interacting transactivator 4 (CITED4)

ACP13737

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13737 Target NameCITED4
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-184Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ96RK1
Background Information
  • Uniprot Id

    Q96RK1

  • Target Species

    Human

  • Target Name

    CITED4

  • Target Full Name

    Cbp/p300-interacting transactivator 4

  • Target Function

    Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Protein Families

    CITED family

  • Target Tissue Specificity

    Expressed in most tissues examined with highest levels of expression in heart, liver, skeletal muscle and pancreas. Also expressed in bladder cell line ECV-304 and in various breast cancer cell lines. Also detected in both in situ and invasive breast tumo

  • Target Synonyms

    AU019445; AW742964; Cbp/p300 interacting transactivator 4; cbp/p300 interacting transactivator; with glu/asp rich carboxy terminal domain; 4; Cbp/p300-interacting transactivator 4; CITE4_HUMAN; Cited4; MRG 2; MRG-2; Mrg2; MSG1 related protein 2; MSG1-related protein 2; Transcriptional co-activator 4

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