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Recombinant Human CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2)

ACP21006

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21006 Target NameCD2BP2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-341Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO95400
Background Information
  • Uniprot Id

    O95400

  • Target Species

    Human

  • Target Name

    CD2BP2

  • Target Full Name

    CD2 antigen cytoplasmic tail-binding protein 2

  • Target Function

    Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=Predominantly nuclear.

  • Target Synonyms

    CD2 (cytoplasmic tail) binding protein 2 ; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; CD2B2_HUMAN; Cd2bp2; FWP010; LIN1; Snu40; U5 snRNP 52K protein; U5-52K

  • Target Background

    This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

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