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| Cat.No | ACP13858 | Target Name | CNOT9 |
|---|---|---|---|
| Target Synonyms | CNOT9; RCD1; RQCD1CCR4-NOT transcription complex subunit 9; Cell differentiation protein RQCD1 homolog; Rcd-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-299 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92600 |
|---|
Uniprot Id
Q92600
Target Species
Human
Target Name
CNOT9
Target Full Name
CCR4-NOT transcription complex subunit 9
Target Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
Target Subcellular Location
Nucleus. Cytoplasm, P-body.
Target Protein Families
CNOT9 family
Target Tissue Specificity
Detected in spleen, thymus, prostate, testis, ovary and intestine.
Target Synonyms
CNOT9; RCD1; RQCD1CCR4-NOT transcription complex subunit 9; Cell differentiation protein RQCD1 homolog; Rcd-1
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