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| Cat.No | ACP11344 | Target Name | CDCA7 |
|---|---|---|---|
| Target Synonyms | CDCA7; JPO1Cell division cycle-associated protein 7; Protein JPO1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-371 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BWT1 |
|---|
Uniprot Id
Q9BWT1
Target Species
Human
Target Name
CDCA7
Target Full Name
Cell division cycle-associated protein 7
Target Function
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
Target Involvement
Immunodeficiency-centromeric instability-facial anomalies syndrome 3 (ICF3)
Target Subcellular Location
Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.
Target Tissue Specificity
Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis.
Target Synonyms
CDCA7; JPO1Cell division cycle-associated protein 7; Protein JPO1
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